We hold a Journal Club on Friday afternoons at 12:30pm in 1320 Anthony Hall, Michigan State University. We cover a range of "hot" topics in the form of recently-published articles, mostly in the stem cell/regenerative medicine/biotechnology domain. Some of the recent papers (and dates covered) include:

12/9/2011: Arnold et.al      Sox2+ Adult Stem and Progenitor Cells Are Important for Tissue Regeneration and Survival of Mice. Cell Stem Cell, 317-329 (2011).

12/2/2011: Miyoshi et.al      Reprogramming of Mouse and Human Cells to Pluripotency Using Mature MicroRNAs. Cell Stem Cell, 8, 633-638 (2011).

11/11/2011: Hishida et.al     Indefinite Self-Renewal of ESCs through Myc/Max Transcriptional Complex-Independent Mechanisms. Cell Stem Cell, 9, 37- 49 (2011).

11/4/2011: Reuveni et.al     Genome-Scale Analysis of Translation Elongation with a Ribosome Flow Model. PLoS Computational Biology, 7(9), e1002127 (2011).

10/21/2011: Sanai et.al     Corridors of migrating neurons in the human brain and their decline during infancy. Nature, 478, 382-386 (2011).

10/2/2011: Kuo et.al     Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity. Nature Cell Biology, 13, 1214-1223 (2011).

9/16/2011: Eguizabel et.al     Complete Meiosis from Human Induced Pluripotent Stem Cells. Stem Cells, 29(8), 1186-1195 (2011).

9/9/2011: Dawlaty et.al     Tet1 Is Dispensable for Maintaining Pluripotency and Its Loss Is Compatible with Embryonic and Postnatal Development. Cell Stem Cell, 9, 166-175 (2011).

8/13/2011: Bedelbaevaa et.al      Lack of p21 expression links cell cycle control and appendage regeneration in mice. PNAS, 107(13), 5845-5850 (2010).

8/5/2011: Pilkus et.al     Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem Cells. Science, 332, 586-589 (2011).

7/29/2011: Hockemeyer et.al     Genetic engineering of human pluripotent cells using TALE nucleases. Nature Biotechnology, 29(8), 731-734 (2011).

7/8/2011: Wilcox et.al     Synaptically-Competent Neurons Derived from Canine Embryonic Stem Cells by Lineage Selection with EGF and Noggin. PLoS One, 6(5), e19768 (2011).

5/20/2011: Gore et.al     Somatic coding mutations in human induced pluripotent stem cells. Nature, 471, 63-67 (2011).

4/22/2011: Anokye-Danso et.al     Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency. Cell Stem Cell 8, 376-388 (2011).

4/8/2011: White et.al      Transparent adult zebrafish as a tool for in vivo transplantation analysis. Cell Stem Cell, 2(2), 183-189 (2008).

3/25/2011: Artyomov, Meissner, and Chakraborty     A Model for Genetic and Epigenetic Regulatory Networks Identifies Rare Pathways for Transcription Factor Induced Pluripotency. PLoS Computational Biology, 6(5), e1000785 (2010).

3/11/2011: Dressel et.al       Pluripotent stem cells are highly susceptible targets for syngeneic, allogeneic, and xenogeneic natural killer cells. FASEB Journal, 24, 2164-2177 (2010).

3/4/2011: Jaskelioff et.al     Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature, 469, 102-106 (2011).

1/21/2011: Szabo et.al     Direct conversion of human fibroblasts to multilineage blood progenitors. Nature, 468(7323), 521-526 (2010).

1/14/2011: Luo et.al     TGF-beta and Insulin Signaling Regulate Reproductive Aging via Oocyte and Germline Quality Maintenance. Cell 143, 299-312 (2010).

12/3/2010: Inoue et.al     Impeding Xist Expression from the Active X Chromosome Improves Mouse Somatic Cell Nuclear Transfer. Science, 330, 496 (2010).

11/19/2010: Kunarso et.al     Transposable elements have rewired the core regulatory network of human embryonic stem cells. Nature Genetics, 42(7), 631-635.

10/22/2010: Kobayashi et.al     Generation of Rat Pancreas in Mouse by Interspecific Blastocyst Injection of Pluripotent Stem Cells. Cell, 142, 787-799 (2010).

8/27/2010: Ohnishi et.al     Small RNA class transition from siRNA/piRNA to miRNA during pre-implantation mouse development. Nucleic Acids Research, 1-11 (2010).

8/20/2010: Ma et.al     MicroRNA Activity Is Suppressed in Mouse Oocytes. Current Biology, 20, 265-270 (2010).

8/6/2010: Donmez et.al      SIRT1 Suppresses -Amyloid Production by Activating the -Secretase Gene ADAM10. Cell, 142, 320-332 (2010).

7/9/2010: Kuhlman and Cox     Site-specific chromosomal integration of large synthetic constructs. Nucleic Acids Research, 38(6), e92 (2010).

6/4/2010: Ahmed et.al      Protein modification and replicative senescence of WI-38 human embryonic fibroblasts. Aging Cell, 9, 252-272 (2010).

4/30/2010: Kragl et.al      Cells keep a memory of their tissue origin during axolotl limb regeneration. Nature, 460, 60-65 (2009).

12/4/2009: Tsubooka et.al      Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts. Genes Cells. 14(6), 683-694 (2009).