Mission

We work towards understanding the mechanisms of cellular reprogramming that governs the transformation of a somatic cell into a pluripotent one. We identify regulatory genes and gene products that govern the state of pluripotency. We use this knowledge to generate human isogenic pluripotent stem cells and to improve the efficiency of somatic cell nuclear transfer.

Eun Ah Chang

Research Scholar
(July 2004– present)

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Dr. Chang received her MD in 1992 from the Medical College of Chung-Ang University, Seoul, Korea where in 2000 she also earned her Ph.D.. Her Ph.D. thesis research was in the clinical significance of p53, MDM2, Cyclin D1 protein expression in patients with Multiple Myeloma. She was working as a Clinical Assistant Professor in the Department of Laboratory Medicine at the University of Korea. Previously her main research there involved Diagnostic Microbiology, Clinical Chemistry and Blood Bank. She was working on the molecular basis of malarial infections in Korean cases by using PCR, RFLP, and denaturing high performance liquid chromatography (DHPLC) method. She was also involved in studying of the relationship between Duffy blood group and Plasmodium vivax. In addition, she was involved in the major project of AFRIMS (Armed Forces Research Institute of Medical Sciences) involving malarial transmission. This project focused on malarial epidemiology which is focused on transmission of malaria from Southern Asia to Eastern Asia. Her research interests are animal and human embryonic Stem Cell culture and neuronal differentiation from human embryonic Stem Cells, neuronal disease and transgenic Animals.