Marie-Claude Senut is a visiting research scientist in the Cellular Reprogramming Laboratory. She earned her PhD at the Universite Pierre et Marie Curie (Paris VI, France) and held a tenured research position at INSERM where she studied the mammalian cholinergic systems during aging and in Alzheimer's disease. She then moved to the University of California San Diego, and then worked at the Salk Institute, the University of Michigan, and Michigan State University. Her research interests are in the study of the mammalian central nervous system and its plasticity in response to injury/disease in the adult and during development. In 2010, she joined the Dr. Douglas Ruden laboratory at Wayne State University and is working at the Cellular Reprogramming Laboratory on experiments aimed at understanding the biological mechanisms of lead (Pb) neurotoxicity. Her research focuses on examining how exposure to Pb results in neural impairment by determining the effects of Pb on DNA methylation profiles and neuronal differentiation of embryonic stem cells.