Mission

We work towards understanding the mechanisms of cellular reprogramming that governs the transformation of a somatic cell into a pluripotent one. We identify regulatory genes and gene products that govern the state of pluripotency. We use this knowledge to generate human isogenic pluripotent stem cells and to improve the efficiency of somatic cell nuclear transfer.

Steve SuhrSteve Suhr

Research Scholar
(August 2006 – present)

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Dr. Suhr earned his Ph.D. from Northwestern University and has worked as a post-doctoral fellow at the University of California-San Diego, The Salk Institute, and the University of Michigan prior to joining the Cellular Reprogramming Laboratory in 2006. His primary focus is on the use of advanced cell and animal models to develop novel therapies for human neurological and neuromuscular diseases that currently have limited effective treatments such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and traumatic brain/spinal cord injury. In the Cibelli Laboratory, he is examining several aspects of cellular differentiation and dedifferentiation, including reprogramming of human somatic cells for production of new cell lines that will more closely mimic the cellular changes that occur in human disease, and developing methods for enhancing the capacity of damaged tissue to participate in regeneration and repair in vivo.